What is CD11b a marker for?
View our protocol for Fluorescent IHC Staining of Frozen Tissue Sections. Interesting work from the Mayo Clinic focused on Alzheimer’s disease (AD) and used the CD11b antibody for both immunoblotting and flow cytometry experiments (3).
What is CD11c a marker for?
CD11c is a widely established marker for dendritic cells (see CD11c protein and function). It can be employed to determine the subsets of dendritic cells (DC) in the immune system (see CD11c expression in human and murine immune system), but CD11c may be more than a marker for DC cells (see CD11c and inflammation).
Do macrophages express CD34?
Besides fibrocytes, CD34 is expressed by hematopoietic precursors, endothelial cells, stromal cells, and may be expressed by macrophages and dendritic cells [6], [31]–[33].
What is B220 marker?
CD19 and B220 (CD45R), an isoform of CD45, are surface markers of mature, resting B cells. CD45 is a tyrosine phosphatase that participates in the modulation of the immune response in both B and T cells. It is present on immature and mature B cells, but it is lost upon differentiation into plasma cells (1–3).
Do T cells express CD11b?
We have found that CD11b, a cell surface integrin of macrophages, granulocytes, and NK cells, is expressed by a subset of CD8+ T cells that include both the active virus-specific CTL and the virus-specific memory CTL populations. Less than 1% of LCMV-immune splenic lymphocytes expressed CD11b.
Do B cells express CD11b?
Conclusion: Memory B cells express CD11b and, in contrast with naive B cells, have high migratory ability. CD11b plays an essential role in the homing process of memory cells.
What is CD38 marker?
CD38 is a multi-functional transmembrane protein that is a lymphocyte receptor and a clinical marker for survival of patients with B-cell chronic lymphocytic leukemia (CLL) [1-5].
What is CD34 marker?
CD34 is a membrane protein that aids cells in cell-cell adhesion. Although little is known about its function, CD34 is an important marker for hematopoietic stem cells (HSCs), muscle satellite cells, and endothelial cells.
Is CD45 a macrophage marker?
The expression of the macrophage markers CD68, CD163 and CD11b, CD45 (a general leukocyte marker), MHCII (expressed by antigen-presenting cells [APCs]), CD11c (dendritic cell marker), lymphatic endothelium hyaluronan receptor-1 (LYVE1; expressed on lymphatic endothelium and macrophage subsets), chemokine receptor 7 ( …