Is TDP 43 a transcription factor?

TDP-43 (TAR DNA binding Protein of 43 kD) is a transcription factor and RNA-binding protein with diverse functions. TDP-43 plays a role in maintaining the precise pattern of spatiotemporal expression of the spermatid-specific Acrv1 gene during spermatogenesis by facilitating RNA polymerase II pausing at the promoter.

What chromosome is the Tardbp gene on?

It is encoded by the TARDBP gene on chromosome 1, and contains a nuclear-localization signal, two RNA-binding motifs, and a glycine-rich region, which contains a “prion-like” domain and mediates protein and heterogeneous nuclear ribonucleoproteins (hnRNP) interactions.

What does Tardbp stand for?

TARDBP (TAR DNA Binding Protein) is a Protein Coding gene. Diseases associated with TARDBP include Amyotrophic Lateral Sclerosis 10 With Or Without Frontotemporal Dementia and Frontotemporal Dementia And/Or Amyotrophic Lateral Sclerosis 1.

What is the full form of DBP?

DBP – Diastolic blood pressure.

What is e vitamin D binding DBP?

Vitamin D binding protein (DBP) is the major carrier protein of 25-hydroxyvitamin D (25(OH) D) in the circulation, where it may serve roles in maintaining stable levels during times of decreased 25(OH) availability and in regulating delivery of 25(OH) D to target tissues.

When was TDP-43 discovered?

TAR DNA binding protein-43 (TDP-43) was identified in 1995 as a repressor protein associated with HIV-1 transcription, which binds to the trans-active response element DNA sequence of the viral genome and is critical for the regulation of the viral gene expression (Ou et al., 1995).

What is DBP price?

Dibutyl Phthalate ( DBP), Grade Standard: Industrial Grade, Rs 130 /kg | ID: 2893242273.

What does retinol binding protein do?

To meet vitamin A requirements of tissues, the liver secretes retinol (vitamin A alcohol) into the circulation bound to its sole specific carrier protein, retinol-binding protein (RBP). The single known function of this protein is to transport retinol from the hepatic stores to target tissues.

What does DBP stand for in biology?

The encoded protein can bind DNA as a homo- or heterodimer and is involved in the regulation of some circadian rhythm genes. [provided by RefSeq, Jul 2014] DBP (D-Box Binding PAR BZIP Transcription Factor) is a Protein Coding gene. Diseases associated with DBP include Hemophilia B .

What does the WWP2 gene do?

GeneCards Summary for WWP2 Gene. WWP2 (WW Domain Containing E3 Ubiquitin Protein Ligase 2) is a Protein Coding gene. Diseases associated with WWP2 include Plantar Fasciitis. Among its related pathways are Ubiquitin-Proteasome Dependent Proteolysis and CFTR-dependent regulation of ion channels in Airway Epithelium (norm and CF).

How does genegenecards work?

GeneCards extracts and integrates gene-related data, including genomic, transcriptomic, proteomic, genetic, clinical, and functional information. This is automatically mined from >100 carefully selected web sources, thereby allowing one-stop access to a very broad information base.