What does secondary ion mass spectrometer do?
Secondary ion mass spectrometry (SIMS) is a technique used to analyze compositions of thin films and surfaces by using a focused primary ion beam to sputter the surface of a sample and analyze the ejected secondary ions.
How does secondary ion mass spectrometry?
Secondary Ion Mass Spectrometer (SIMS) Instrumentation – How Does It Work? the electrostatic filter reduces the energy range of the secondary ions so that they can then be separated into independent ion beams (based on the charge/mass ratio) by passing them through a magnetic field (magnetic sector).
How does mass spec work?
A mass spectrometer can measure the mass of a molecule only after it converts the molecule to a gas-phase ion. To do so, it imparts an electrical charge to molecules and converts the resultant flux of electrically charged ions into a proportional electrical current that a data system then reads.
Is mass spec specific?
Mass spectrometry data analysis is specific to the type of experiment producing the data. This is often important in determining the neutral mass but it also indicates something about the nature of the molecules. Different types of ion source result in different arrays of fragments produced from the original molecules.
What does Maldi ToF measure?
Mass spectrometry is an analytical technique in which samples are ionized into charged molecules and ratio of their mass-to-charge (m/z) can be measured.
What is the difference between static and dynamic SIMS?
Static SIMS focuses solely on the first top monolayer, mostly for molecular characterization. Dynamic SIMS mode investigates bulk composition and in-depth distribution of trace elements, with a depth resolution from sub-nm to tens of nm. All CAMECA SIMS instruments are capable of dynamic SIMS.
What is ToF in analysis?
Time-of-Flight Secondary Ion Mass Spectrometry (ToF-SIMS) is a surface-sensitive analytical method that uses a pulsed ion beam (Cs or microfocused Ga) to remove molecules from the very outermost surface of the sample. The particles are removed from atomic monolayers on the surface (secondary ions).
What does mass spec tell you?
Mass spectrometry is an analytical tool useful for measuring the mass-to-charge ratio (m/z) of one or more molecules present in a sample. These measurements can often be used to calculate the exact molecular weight of the sample components as well.
Is mass spec expensive?
Mass spectrometry (MS) in clinical laboratories has a reputation for being both time intensive and costly. These are two potential factors that have influenced the lack of take-up of the technology.
Why is MALDI-TOF used?
Matrix-assisted laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry (MS) has become a widely used technique for the rapid and accurate identification of bacteria, mycobacteria and certain fungal pathogens in the clinical microbiology laboratory.