How is pulmonary toxicity treated?
While there is no specific treatment to reverse lung damage, your doctor may prescribe medications or therapies to help manage the symptoms of lung toxicity. Corticosteroids: Steroids work by decreasing inflammation and relieve the cough and some pain associated with lung toxicity.
What chemo drug causes pulmonary toxicity?
Any chemotherapeutic drug can adversely affect the lung, but the drugs most commonly implicated in lung toxicity are bleomycin, carmustine, busulfan, and cyclophosphamide [43-46]. Approximately 1-10% of patients taking one of these drugs are affected. Bleomycin is the drug most commonly studied as a cause of DILD.
Is there an alternative to oxaliplatin?
An alternative strategy would be to discontinue oxaliplatin before neurotoxicity becomes apparent and continue with fluoropyrimidine and bevacizumab instead. For maintenance therapy, a number of studies are looking at the efficacy of single-agent bevacizumab aft er induction therapy.
Can Xeloda cause lung problems?
Conclusions: Pulmonary fibrosis is a rare complication of oxaliplatin and capecitabine/5-fluorouracil.
How long can you live with scarred lungs?
When you do your research, you may see average survival is between three to five years. This number is an average. There are patients who live less than three years after diagnosis, and others who live much longer.
What is the most common drug-induced respiratory problem?
Interstitial pneumonitis (ie, inflammation of the lung interstitium, such as the alveolar septa) is the most common manifestation of drug-induced lung disease. A wide array of drugs can cause interstitial pneumonitis.
Can lung Damage From Chemo be reversed?
While there is no specific treatment to reverse lung damage, your doctor may prescribe medications or therapies to help manage the symptoms of lung toxicity.
What are the long term side effects of oxaliplatin?
Hand/foot numbness/tingling appeared to be the longest lasting side-effects for those treated with oxaliplatin. The odds of hand numbness/tingling were significantly greater for the FLOX group during therapy and, while no longer significant at 18 months, were significantly greater at the long-term endpoint.
How many cycles of oxaliplatin can you have?
Depending on your needs, you may have between 6 and 8 cycles. You have oxaliplatin as a drip into your bloodstream over 2 hours. You take capecitabine tablets twice a day.
How long can you stay on XELODA?
Your Xeloda therapy is made up of a series of treatment cycles which usually lasts for 21 days. Your doctor will advise you how many cycles of treatment you will have and whether there are any rest days in the cycle.
What happens when you stop taking XELODA?
fast your blood clots, and can cause bleeding that can lead to death. This can happen as soon as a few days after you start taking XELODA, or later during treatment, and possibly even within 1 month after you stop taking XELODA. Your risk may be higher because you have cancer, and if you are over 60 years of age.