What other regimens can be used in the treatment of breast cancer?
Chemotherapy drugs used for breast cancer
- Anthracyclines, such as doxorubicin (Adriamycin) and epirubicin (Ellence)
- Taxanes, such as paclitaxel (Taxol) and docetaxel (Taxotere)
- 5-fluorouracil (5-FU) or capecitabine.
- Cyclophosphamide (Cytoxan)
- Carboplatin (Paraplatin)
What is the difference between adjuvant and first line therapy?
The two therapies differ largely in when they are given and why. Neoadjuvant therapies are delivered before the main treatment, to help reduce the size of a tumor or kill cancer cells that have spread. Adjuvant therapies are delivered after the primary treatment, to destroy remaining cancer cells.
What drugs are used in adjuvant chemotherapy?
If you have HER2 breast cancer, you may have a targeted therapy called trastuzumab with your chemotherapy. Sometimes the targeted therapy drug pertuzumab (Perjeta®) is given in combination with trastuzumab and chemotherapy. The combination may be used before surgery if there is a high risk of the cancer coming back.
What is adjuvant treatment in cancer?
Listen to pronunciation. (A-joo-vunt THAYR-uh-pee) Additional cancer treatment given after the primary treatment to lower the risk that the cancer will come back. Adjuvant therapy may include chemotherapy, radiation therapy, hormone therapy, targeted therapy, or biological therapy.
What is the easiest breast cancer to treat?
Invasive breast cancers are staged I through IV, with stage I being the earliest stage and easiest to treat, while stages II and III represent advancing cancer, with stage IV representing breast cancer cells that have spread (metastasized) to distant organs like the bones, lungs, or brain.
What are the side effects of adjuvant chemotherapy?
What are the side effects of adjuvant or neoadjuvant chemotherapy?
- nausea, vomiting.
- fatigue.
- hair loss.
- bruising and bleeding easily.
- mouth sores, dry mouth.
- infection.
- anemia.
- loss of appetite.
What is 1st line treatment?
First-line treatment or therapy simply refers to the initial, or first treatment recommended for a disease or illness. This may also be referred to as primary treatment, initial treatment, or induction therapy. With many conditions, including cancer, there are many possible treatments that could be effective.
How long is adjuvant chemotherapy?
Adjuvant treatments may last from just a few weeks to as long as 10 years.
Should I have adjuvant chemotherapy?
Your doctor may recommend adjuvant chemotherapy if: you have a particular type of cancer or carry certain biomarkers that are known to respond well to chemotherapy drugs. you carry specific genetic mutations that carry a high risk of cancer recurrence. during surgery, cancer cells were found in your lymph nodes.
Who gets adjuvant chemo breast cancer?
Adjuvant chemotherapy should be offered to patients whose breast cancer is of high enough risk that the patient and the physician accept the associated toxic effects. Indications generally include tumors greater than 1 cm, node-positive disease, or ER-negative cancers.