Can you have sickle cell and beta thalassemia?

Can you have sickle cell and beta thalassemia?

One parent carries sickle trait, which causes no health problems for him or her. The other carries the trait for beta+ thalassemia, which sometimes causes a mild anemia (low blood count), but usually no symptoms. When these traits come together in the same person, the result is sickle-beta+-thalassemia.

What is beta thalassemia plus?

Sickle Beta Plus Thalassemia (Sβ+ thalassemia) is a “mild” form of sickle cell disease. Your child’s red blood cells have only a small amount of the normal hemoglobin called hemoglobin A. They also have abnormal hemoglobin called hemoglobin S (sickle hemoglobin).

Do beta thalassemia carriers have symptoms?

People with beta thalassemia trait usually do not have any symptoms. Children with beta thalassemia intermedia or major may not show any symptoms at birth, but usually develop them in the first 2 years of life.

What are the side effects of beta thalassemia?

Beta thalassemia major causes major problems and can result in early death. Complications may include delayed growth, bone problems causing facial changes, liver and gall bladder problems, enlarged spleen, enlarged kidneys, diabetes, hypothyroidism, and heart problems.

Which is worse sickle cell or thalassemia?

Sickle beta zero thalassemia (no normal hemoglobin) is usually associated with a worse prognosis and more severe disease course than sickle beta plus thalassmia (a reduced amount of normal hemoglobin).

What part of the body does thalassemia affect?

Thalassemia can cause bone deformities in the face and skull. People who have thalassemia may also have severe osteoporosis (brittle bones). Too much iron in your blood. This can cause damage to the heart, liver, or endocrine system (glands in the body that make hormones, like the thyroid gland and adrenal glands).

Can thalassemia cause weight gain?

They do not gain weight and grow at the expected rate (failure to thrive) and may develop yellowing of the skin and whites of the eyes (jaundice). Affected individuals may have an enlarged spleen, liver, and heart, and their bones may be misshapen. Some adolescents with thalassemia major experience delayed puberty.

What happens if two people with thalassemia have kids?

If you have thalassemia and your partner carries the trait for thalassemia, there is a chance that your baby may inherit the disease. The stress of pregnancy can make the symptoms of thalassemia worse and cause complications such as anemia and stress on the heart.

Is sickle cell curable?

Stem cell or bone marrow transplants are the only cure for sickle cell disease, but they’re not done very often because of the significant risks involved. Stem cells are special cells produced by bone marrow, a spongy tissue found in the centre of some bones.

Is thalassemia the same as sickle cell anemia?

Thalassemia is not same as sickle cell anemia disease. They both are different, in sickle cell anemia, the shape of the RBCs or the red blood corpuscles are sickle shaped, which are unable to carry sufficient amount of oxygen to the other body cells, whereas in case of Thalassemia there is lack…

What is beta zero thalassemia?

Sickle beta-zero thalassemia is a form of sickle cell disease. It describes the condition resulting from a hybrid of two genetic defects in the gene for making hemoglobin – an essential component of red blood cells.

What is the treatment for sickle – cell anemia?

Treating complications. Physicians treat most complications of sickle cell anemia as they take place. Treatment may include antibiotics, vitamins, blood transfusions, pain-relieving medicines, other medications and perhaps surgery, such as to fix vision problems or to get rid of a harmed spleen.

What are the statistics of sickle cell disease?

Sickle cell disease is the most common inherited blood disorder in the United States, affecting 70,000 to 80,000 Americans. The disease is estimated to occur in 1 in 500 African Americans and 1 in 1,000 to 1,400 Hispanic Americans.