What is the main cause of avascular necrosis?

Avascular necrosis is a disease that results from the temporary or permanent loss of blood supply to the bone. It happens most commonly in the ends of a long bone. Avascular necrosis may be the result of injury, use of medicines, or alcohol. Symptoms may include joint pain and limited range of motion.

What are the consequences of avascular necrosis of the femoral head?

Legg-Calve-Perthes is idiopathic avascular necrosis of the femoral head that affects pediatric populations. Lack of blood supply causes necrosis of the femoral head leading to a deformity that puts the patient at high risk of developing osteoarthritis and/or losing range of motion (ROM).

Is avascular necrosis a genetic disorder?

Most cases of avascular necrosis of the femoral head (ANFH) are not inherited in families. In a few rare families, ANFH is inherited in an autosomal dominant pattern. All individuals inherit two copies of each gene .

Is Crohn’s disease associated with avascular necrosis of femoral head?

Avascular necrosis (osteonecrosis) occurs in Crohn’s disease, but the rate of this particular complication is not known. Over 20 years, 877 patients with Crohn’s disease, 492 women (56.1%) and 385 men (43.9%), were evaluated with patient follow-up data available for a mean of 7.8 years.

What happens when the femoral head collapse?

Osteonecrosis of the hip develops when the blood supply to the femoral head is disrupted. Without adequate nourishment, the bone in the head of the femur dies and gradually collapses. As a result, the articular cartilage covering the hip bones also collapses, leading to disabling arthritis.

Is AVN an autoimmune disease?

Systemic lupus erythematosus (SLE) is an autoimmune, chronic inflammatory multisystem connective tissue disease and AVN of bone is a well recognized complication of SLE [3].

What is femoral head necrosis?

Avascular necrosis (AVN) of the femoral head is a pathologic process that results from interruption of blood supply to the bone. AVN of the hip is poorly understood, but this process is the final common pathway of traumatic or nontraumatic factors that compromise the already precarious circulation of the femoral head.

Is avascular necrosis serious?

Avascular necrosis is a localized death of bone as a result of local injury (trauma), drug side effects, or disease. This is a serious condition because the dead areas of bone do not function normally, are weakened, and can collapse.

Is AVN a disability?

Under Social Security Disability (SSDI) guidelines, there is no “listing” for AVN, and having AVN does not automatically entitle you to long-term disability (LTD) under SSDI or under a group disability plan provided by an employer (ERISA).