What is the classification for gemfibrozil?

Gemfibrozil is in a class of lipid-regulating medications called fibrates. It works by reducing the production of triglycerides in the liver.

Is Lopid the same as gemfibrozil?

Gemfibrozil (Lopid) is a fibrate, which is a class of medications that help with cholesterol problems, especially high triglycerides. Statins also help with cholesterol problems but work differently than gemfibrozil (Lopid).

What is the mechanism of action of gemfibrozil?

Mechanism of Action: Activation of the nuclear transcription receptor “peroxisome proliferator – activated receptor alpha” (PPAR-α). PPAR-α activation by fibrates results in numerous changes in lipid metabolism that act together to decrease plasma triglyceride levels & increase plasma HDL.

What is the trade name for gemfibrozil?

What is gemfibrozil? Gemfibrozil is a prescription drug. It comes as a tablet you take by mouth. Gemfibrozil is available as the brand-name drug Lopid.

Is gemfibrozil bad for your liver?

Introduction. Gemfibrozil is a fibric acid derivative used in the therapy of hypertriglyceridemia and dyslipidemia. Gemfibrozil therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury.

Is gemfibrozil hard on the kidneys?

Warnings for people with certain health conditions For people with kidney problems: Gemfibrozil may make your kidney disease worse. If you have kidney failure, you should not use gemfibrozil. For people with heart disease: Gemfibrozil has not been shown to decrease your risk of death from heart disease.

Can I lose weight on gemfibrozil?

Results: With gemfibrozil significantly more subjects lost weight (51.7% versus 38.6%, P<0.0001) and significantly fewer subjects gained weight (42.5% versus 54.0%, P<0.0001) than with placebo.

What drugs interact with gemfibrozil?

Some products that may interact with this drug include: asunaprevir, “blood thinners” (such as warfarin), colchicine, repaglinide, “statin” drugs (such as atorvastatin, lovastatin, simvastatin). This medication can slow down the removal of other medications from your body, which may affect how they work.

What are side effects of gemfibrozil?

The more common side effects that can occur with use of gemfibrozil include:

• stomach upset.
• stomach pain.
• nausea.
• vomiting.
• diarrhea.
• constipation.
• rash.
• dizziness.

Does gemfibrozil cause memory loss?

Gemfibrozil, used for elevated cholesterol, also is reported to cause memory disorders, as are the more commonly used class of cholesterol drugs, the statins.

Can gemfibrozil cause weight gain?

Both a greater loss and smaller gain in weight with gemfibrozil were age-related and significant in subjects > or =66 years (median age), but not in younger subjects. Weight change was paralleled by changes in insulin.

Does gemfibrozil make you gain weight?

How much gemfibrozil is in a Lopid tablet?

LOPID® (gemfibrozil tablets, USP) is a lipid regulating agent. It is available as tablets for oral administration. Each tablet contains 600 mg gemfibrozil.

What do you need to know about Lopid tablets?

Lopid Description Lopid® (gemfibrozil tablets, USP) is a lipid regulating agent. It is available as tablets for oral administration. Lopid is a lipid regulating agent which decreases serum triglycerides and very low density lipoprotein (VLDL) cholesterol, and increases high density lipoprotein (HDL) cholesterol.

What is the melting point of gemfibrozil tablets?

The melting point is 58° –61°C. Gemfibrozil is a white solid which is stable under ordinary conditions. Indications & Dosage INDICATIONS LOPID (gemfibrozil tablets, USP) is indicated as adjunctive therapy to diet for: 1.

What’s the generic name for the drug Lopid?

Lopid Generic Name: gemfibrozil (jem FYE broe zil)