What is the chemical name of erythromycin?

(3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-6- {[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy}- 14-ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)- 5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy}- 3,5,7,9,11,13-hexamethyl-1-oxacyclotetradecane-2,10-dione
Erythromycin/IUPAC ID

What is erythromycin made up of?

Standard-grade erythromycin is primarily composed of four related compounds known as erythromycins A, B, C, and D. Each of these compounds can be present in varying amounts and can differ by lot. Erythromycin A has been found to have the most antibacterial activity, followed by erythromycin B.

What is the combination of erythromycin?

The combination of erythromycin and sulfisoxazole (a sulfa drug) is used to treat certain ear infections caused by bacteria. It usually is used in children. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

What is the chemical structure of erythromycin?

Erythromycin A is an erythromycin that consists of erythronolide A having 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranosyl and 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranosyl residues attahced at positions 4 and 6 respectively. It is an erythromycin and a cyclic ketone.

What type of antibiotic is erythromycin?

This medicine is also used to prevent recurrent attacks of rheumatic fever in patients who have had an allergic reaction to penicillin or sulfa drugs. Erythromycin belongs to the class of medicines known as macrolide antibiotics. It works by killing bacteria or preventing their growth.

Which of the following species is used to producing erythromycin?

erythromycin, drug synthesized by the soil bacterium Streptomyces erythraeus and used in the treatment of throat infections, pneumonia, and other diseases.

What is the main function of erythromycin?

Erythromycin is used to prevent and treat infections in many different parts of the body, including respiratory tract infections, skin infections, diphtheria, intestinal amebiasis, acute pelvic inflammatory disease, Legionnaire’s disease, pertussis, and syphilis.

Is erythromycin natural or synthetic?

Macrolide antibiotics, represented by erythromycin A (1), are large polyketide natural products and their semisynthetic derivatives.

Is erythromycin sulfa based?

Sulfa-containing drugs include: sulfonamide antibiotics, including sulfamethoxazole-trimethoprim (Bactrim, Septra) and erythromycin-sulfisoxazole (Eryzole, Pediazole)

Is erythromycin penicillin based?

Erythromycin is an antibiotic. It can be taken by people who are allergic to penicillin. Space your doses out evenly over the day and complete the full course of this antibiotic, even if you feel your infection has cleared up. The most common side-effects are feeling sick (nausea) and tummy (abdominal) discomfort.

What is the difference between tetracycline and erythromycin?

Both drugs reduced acne severity to the same extent. Pustules, papules, and open comedo counts decreased significantly over the 12-week period. Seventy-seven percent of the erythromycin-treated patients and 89% of the tetracycline-treated patients stated that their acne was markedly improved or improved by week 12.

What type of drug is erythromycin?

Erythromycin. Erythromycin is a Macrolide and Macrolide Antimicrobial. The physiologic effect of erythromycin is by means of Decreased Sebaceous Gland Activity. The chemical classification of erythromycin is Macrolides. Erythromycin is a broad-spectrum, macrolide antibiotic with antibacterial activity.

Is erythromycin a macrolide?

Erythromycin is a bacteriostatic antibiotic macrolide produced by Streptomyces erythreus. Erythromycin A is considered its major active component. In sensitive organisms, it inhibits protein synthesis by binding to 50S ribosomal subunits.

How is erythromycin metabolized and eliminated from the body?

Most of erythromycin is metabolised by demethylation in the liver by the hepatic enzyme CYP3A4. Its main elimination route is in the bile with little renal excretion, 2%-15% unchanged drug. Erythromycin’s elimination half-life ranges between 1.5 and 2.0 hours and is between 5 and 6 hours in patients with end-stage renal disease.

What drugs should not be taken with erythromycin?

Hence, erythromycin should not be administered to people using these drugs, or drugs that also prolong the QT interval. Other examples include terfenadine (Seldane, Seldane-D), astemizole (Hismanal), cisapride (Propulsid, withdrawn in many countries for prolonging the QT time) and pimozide (Orap).